Department of Agricultural Biotechnology, National Agricultural Biotechnology Research Center, P.O. Box: 31, Holeta, Ethiopia

Publications

• Review Article   
  Gene editing and effect of ANP32 proteins splicing variant for viral replication: A review
  Author(s): D Mengistie*
  
  Because of the expanding human population, we must produce more food while lessening the environmental impact of farming. Cattle productivity has been revolutionized by selective breeding and genomic selection. Currently, transgenic and genome-editing technologies have promising prospects for producing cattle that are healthier and more productive. The 220-291 amino acid proteins that make up the acidic leucine-rich nuclear phosphoprotein 32 kDa (ANP32) family have been evolutionarily conserved and are distinguished by a Low Complexity Acidic Region (LCAR) at the C-terminus and an N-terminal Leucine-Rich Repeat domain (LRR). Numerous physiological processes, such as chromatin remodeling, apoptosis, and nervous system development, are regulated by proteins belonging to the ANP32 family. Tumorigenesis and abnormal ANP32 expression are tightly associated. The ANP32 family proteins' a.. Read More»
  DOI: 10.15651/2408-5502.25.12.019

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