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Serum Calcitonin Gene-Related Peptide (CGRP) Levels in Migraine: A Study on its Clinical Correlation and Diagnostic Efficacy

Abstract

Mohammed Zoheb, Sofia Khatoon, Noorunissa Begum, Hafeeza Sultana, Maryam Rashed, Sara Shreen, Syed Iqbal Ahmed, Aleem Ahmed Khan,

Migraine is a primary headache disorder marked by recurrent unilateral headache episodes. Calcitonin gene related peptide (CGRP) plays major role in migraine pathophysiology. CGRP is multifunctional, and its vasodilating activity within the central and peripheral blood vessels is one in all its primary functions. The intention is to prove serum calcitonin gene related peptide (CGRP) as an early diagnostic tool for migraine and the novelty is to correlate it with characteristics of migraine so that it helps in early initiation of treatment.

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