Epidemiological profiling of multiple sclerosis and creating its database in Nepal


Ayush Chandra and Avinash Chandra

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory neurological disease of the central nervous system (CNS). MS attacks the myelinated axons in the CNS, destroying the myelin and the axons to varying degrees. Although, MS is not a newly recognized disorder of nervous system, but a frequent diagnosis of MS started only 2-3 decades ago. Many epidemiological studies have been performed in Europe, North America, Canada and Australia where the prevalence of MS seems to be high, and recent studies show an increase in the disease prevalence in such regions. The prevalence is thought to be from 0 to 20 per 100,000 populations in Asia-Pacific region. In this part of the world, MS is at large an unknown, under-diagnosed disease in terms of its incidence, prevalence. Till now, no prevalence study has been done in Nepal. Its nature is not well known even in medical person’s knowledge in Nepal. Hence this study is most needed for Nepal’s scenario of MS.


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