Cornelia de Lange Syndrome

Abstract

Sujatha S Reddy, Shwetha V, Pallavi Chauhan, Sahana K

Cornelia de Lange Syndrome (CdLS) is a rare congenital disease, characterized by psychomotor retardation associated with series of malformations . The main clinical features include delay in growth and development, hirsutism, structural anomalies in the limbs and distinctive facial characteristics. It affects both the physical and intellectual development of the child. Dental problems include: ogival palate, micrognathia, dental malalignment, delayed teething, microdontic teeth, periodontal disease and dental erosion produced by gastric reflux.