Abstract

B.T.Saatov

Vitiligo is an acquired chronic disease of human skin, characterized by the appearance of depigmentation foci on the skin due to the absence or sharp decrease in the pigment melanin content. According to WHO, there are currently 40 million people suffering from vitiligo in the world. It occurs regardless of race, gender, or age (1,2).Epidemiological studies conducted in recent years unequivocally indicate an intensive increase in the number of vitiligo patients throughout the world, including in Uzbekistan (3).The observed intensive increase in the incidence of vitiligo among children, young people, people of working age, as well as a significant reduction in the quality of life of patients gives this dermatosis a certain social value.

Despite this, still many issues of the etiopathogenesis of vitiligo remain unresolved, and treatment methods are imperfect. In this regard, the study of the molecular mechanisms of the emergence and development of vitiligo and on the basis of the results obtained, the development of new approaches to its pathogenetic therapy is an important task of modern medical and biological science