Reversible thyrotoxicosis-induced cardiomyopathy: a clinical case


Biktashev D.B

The purpose of this interesting case is to present a case of cardiomyopathy caused by Graves thyrotoxicosis. This is the case of a 25-year-old man with severe symptomatic congestive heart failure, who was subsequently diagnosed with dilated cardiomyopathy, secondary to Graves' disease. Despite the fraction of systolic ejection of the left ventricle of 11% on echocardiography, treatment with antithyroid drugs led to a rapid improvement in its clinical status and normalization of the ejection fraction. The proposed mechanisms underlying the development of systolic dysfunction in thyrotoxicosis are discussed , and literature on similar cases reported earlier is also highlighted. Cardiomyopathy should be considered even in young patients with Graves thyrotoxicosis. As far as we know, this is the youngest patient in the literature who has dilated cardiomyopathy caused by Graves thyrotoxicosis.


Share this article